N,N-bis(2-chloroethyl)carbamate tert-butyl ester ingagwiritsidwe ntchito ngati gawo lapakati pa mankhwala ndi kapangidwe ka organic. Mu kusintha kwa kapangidwe ka organic, gulu la Boc lomwe lili mu kapangidwe kake limatha kuchotsedwa mosavuta kuti pakhale gulu la carboxyl logwira ntchito.

Njira yopangira imaphatikizapo kusakaniza mwachangu kuyimitsidwa kwa bis-(2-chloroethyl)amine hydrochloride (5 g, 0.028 mol) mu dichloromethane (42 mL) ndi10% sodium hydroxide aqueous solution (28 mL) pa kutentha kwa ayezi. Yankho la di-tert-butyl dicarbonate (6.11 g, 0.028 mol) mu dichloromethane (28 mChemicalbook L) imawonjezedwa. Pambuyo posakaniza kutentha kwa chipinda kwa maola 18.5, dichloromethane (30 mL) imawonjezedwa pang'onopang'ono ku chisakanizo cha reaction. Magawo awiriwa amalekanitsidwa. Gawo lamadzi limachotsedwanso ndi dichloromethane (30 mL). Magawo ophatikizika a organic amaumitsidwa pa anhydrous magnesium sulfate, kusefedwa, ndikusungunuka kuti mupeze N,N-bis(2-chloroethyl)carbamate tert-butyl.