2,4-Difluoroaniline

CAS367-25-9

Mankhwala: mafuta achikasu chopepuka.

Ntchito: 2,4-Difluoroaniline ndi mankhwala apakatikati pa kapangidwe ka zinthu zachilengedwe. Mu mankhwala, imagwiritsidwa ntchito popanga difluorophenylsalicylic acid ndi polyfluorodiphenyl acid. Difluorophenylsalicylic acid ndi mankhwala oletsa kutupa omwe si a carboxylic acid (NSAID), omwe ali ndi dzina losavomerezeka padziko lonse lapansi (INN) Diflunisal. Chochokera chatsopanochi cha salicylic acid, ngakhale chilibe gulu la acetyl la aspirin, chili ndi gulu la difluorophenyl, zomwe zimapangitsa kuti pakhale zotsatirapo zochepa za antiplatelet, kusagwira bwino ntchito m'mimba, komanso kugwira ntchito kwa maola 8-12. Ikhoza kukhala mankhwala odalirika kwambiri a salicylic acid. Ndi mankhwala ofunikira kwambiri pakupanga mankhwala ophera tizilombo.

Fomula ya molekyulu C6H5F2N,

kulemera kwa molekyulu 129.11,

Nambala ya EINECS 206-687-5

Malo osungunuka -7.5 °C (lit.)

Malo otentha 170 °C/753 mmHg (lit.)

Kuchulukana 1.268 g/mL pa 25 °C (lit.)

Chizindikiro cha refractive n20/D 1.506 (lit.)

Malo owunikira 145 °F

Njira Yopangira 1. Njira Yochepetsera 2,4-Difluoronitrobenzene: Ufa wachitsulo ndi ammonium chloride wamadzimadzi amawonjezedwa ku reduction reactor, kutenthedwa kuti abwerere m'thupi, kenako 2,4-difluoronitrobenzene imawonjezedwa pang'onopang'ono. Pambuyo powonjezera, reflux kwa maola awiri. Pambuyo pochitapo kanthu, mankhwalawa amasungunuka ndi nthunzi, kulekanitsidwa ndi Chemicalbook, ndikuumitsidwa ndi calcium chloride kuti apeze mankhwala oyenerera omwe ali ndi phindu la 87%. 2. Amapezedwa kuchokera ku 1,2,4-trichlorobenzene kudzera mu nitration, fluorination, ndi reductive dechlorination; kapena amapezeka kuchokera ku m-phenylenediamine kudzera mu diazotization, substitution, nitration, ndi reduction.

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