Dimethylformamide (chidule cha DMF), chomwe chimadziwikanso kuti N,N-dimethylformamide, ndi cholowa m'malo mwa formamide ndi dimethyl, ndipo magulu onse awiri a methyl ali pa maatomu a N (nayitrogeni), kotero ndi dzina lake. Monga mankhwala ofunikira komanso zosungunulira zabwino kwambiri, DMF imagwiritsidwa ntchito kwambiri mu polyurethane, acrylic, zowonjezera chakudya, mankhwala, mankhwala ophera tizilombo, utoto, zamagetsi ndi mafakitale ena.

DMF ndi madzi opanda mtundu komanso owonekera bwino okhala ndi malo otentha kwambiri, malo ozizira ochepa, kukhazikika kwa mankhwala ndi kutentha, ndipo amasakanikirana ndi madzi ndi zinthu zambiri zachilengedwe. Ndi chinthu chosungunulira chomwe chimagwiritsidwa ntchito kwambiri pakuchita kwa mankhwala ndipo chimatchedwa "chosungunulira chapadziko lonse lapansi": DMF imagwiritsidwa ntchito. Ulusi wa acrylic womwe umapangidwa ndi njira yowuma yozungulira ya ulusi wa acrylic wokhala ndi zosungunulira uli ndi mawonekedwe a hydrophobicity yabwino, mphamvu yophimba mwamphamvu, kapangidwe kofewa, komanso kumva kwamphamvu kwa manja; popanga chikopa chopangidwa ndi polyester chonyowa, DMF ingagwiritsidwe ntchito ngati chotsukira ndi chotsukira cha polyurethane resin. Imagwiritsidwa ntchito popaka zinthu zosiyanasiyana zotambasuka, ndipo ikagwiritsidwa ntchito popaka utoto wa chikopa, imatha kupanga mtundu wa chikopa kukhala wofanana komanso wosatha; chifukwa cha mphamvu yake yosungunuka, DMF imagwiritsidwa ntchito ngati chosungunulira mu utoto ndipo imagwiritsidwa ntchito popaka utoto ulusi wopangidwa, zomwe zingathandize kuti chikopa chikhale chofanana. Kapangidwe ka utoto; monga chosungunulira chosankha chomwe chimagwiritsidwa ntchito polekanitsa, DMF ingagwiritsidwe ntchito poyamwa ma hydrocarbon osiyanasiyana ndi mpweya wosapangidwa. Mwachitsanzo, DMF imagwiritsidwa ntchito kutsuka ethylene kuti ichotse acetylene, motero imayeretsa ethylene. DMF ingagwiritsidwenso ntchito kuchotsa isoprene, piperylene, ndi zina zotero kuchokera ku mpweya wotulutsa utsi wa chomera cha ethylene kuti ipange utomoni wosatupitsidwa; DMF ingagwiritsidwenso ntchito ngati chosungunulira chosankha cha njira zotulutsira mafuta m'munda wa kukonza mafuta. Mwachitsanzo: m'machitidwe a polycarboxylic acid omwe ali ndi makhalidwe ofanana ndipo ndi ovuta kuwalekanitsa, monga isophthalic acid ndi terephthalic acid, amatha kulekanitsidwa mosavuta ndi kuchotsa DMF solvent kapena recrystallization stepwise.

Mu zochita zachilengedwe, dimethylformamide siigwiritsidwa ntchito kwambiri ngati chosungunulira cha reaction, komanso ndi chinthu chofunikira kwambiri popanga zinthu zachilengedwe. Mu makampani opanga mankhwala, ngati mankhwala opangira, imagwiritsidwa ntchito kwambiri popanga mankhwala a doxycycline, cortisone, ndi sulfonamide; mumakampani opanga mankhwala ophera tizilombo, imagwiritsidwa ntchito popanga mankhwala ophera tizilombo komanso ophera tizilombo omwe amagwira ntchito bwino komanso opanda poizoni wambiri.

Monga njira yopangira mankhwala, DMF ingagwiritsidwe ntchito ngati chosungunulira cha kristalo poyeretsa mankhwala. Mu makampani a zamagetsi, ingagwiritsidwe ntchito kusintha kukhuthala kwa chotsukira cha laminates zokhala ndi mkuwa. DMF ingagwiritsidwenso ntchito ngati chosungunulira chonyamulira kupanga kristalo ya polymeric yokhala ndi BF3 (boron trifluoride), zomwe zimapangitsa BF3 kusintha kuchoka pa mpweya kukhala yolimba komanso yosavuta kunyamula. Monga chosungunulira cha polar (hydrophilic) aprotic chokhala ndi malo otentha kwambiri, chingathandize njira ya bimolecular nucleophilic substitution reaction (SN₂). Kuphatikiza apo, dimethylformamide imakhala ndi mphamvu yothandiza pa hydrogenation, dehydrogenation, dehydration ndi dehydrohalogenation reactions, zomwe zimachepetsa kutentha kwa reaction ndikuwongolera kuyera kwa mankhwala.

Zikuwoneka kuti DMF ndiyoyenera kutchedwa "Universal solvent". Mitundu yosiyanasiyana ya ntchito izi idzakhala yovuta kuiposa pakapita nthawi yochepa.

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